Rh Negative refers to the absence of the Rhesus factor, a specific protein found on the surface of red blood cells. People with Rh Negative blood type do not have this protein, which can affect blood transfusions and pregnancy. The most common blood types are A, B, AB, and O, and each can be either Rh positive or Rh negative. Approximately 15% of the global population is Rh Negative. This trait is more prevalent in certain populations, such as those of European descent. Understanding Rh Negative status is important for medical procedures and ensuring compatibility in blood transfusions.